Our Droid DNA has an unlocked bootloader and we are able to flash Roms and kernels, but the process can be a pure headache thanks to the Security ON or S-ON that HTC has built in. With S-ON we have to manually flash unstable boot.imgs when flashing Roms or risk bootloops and soft-bricks. A company "MobileTechVideos" has a JTAG method to provide S-OFF. The company will charge $45 to jTAG the DNA plus you will pay to ship it to them and $10-45 to ship the phone back to yourself. This seems kind of highway roberish to me, but if you are willing to fork out these kinds of funds for S-OFF more power to you. I guess in the long run you will save money since you won't be purchasing as much ADVIL!
Via MobileTechVideos