I really hate to try and stir this up again, but I'm assuming the general GPS failures from time to time are prevalent in any low-power application of a GPS chip such as these ones, and no smartphone (iPhone, Pre, etc) is immune, but it's happened a total of three different times in the past two days to me. First two it took 10 minutes to find the tower, and then today I was running late, and as it was docked in my Seidio Innotraveler, it took the entire trip (~45 minutes) and still never found my location.
I do have Weatherbug installed, so I disabled it's usage of any GPS and just manually entered my zip code (should help with battery a little, too), and I also disabled cell tower location as one of the suggested fixes. Any other ideas? After I rooted, I did *228-2'd it a couple times, I had some voice data issues, so I should have a fairly up-to-date PRL whatever it may be (but do I even need a PRL at this point since I disabled data location lookup?) I'm trying to have my droid replace my Garmin Nuvi, but if I'm taking a trip to somewhere I have no clue where it's at, I'd hate to be stranded because my stupid phone's GPS decided to stop working.