I've had my DNA for about two weeks, and love it!
The screen is simply stunning, the device is amazingly fast, and it feels great in your hand. I looked at the Samsung Note2, and while it does have some great features and a beautiful screen, I just couldn't see carrying it around all day! One thing you do more then anything else, with a cell phone, is CARRY IT! I also love the built in inductive (wireless) charging capabilities.
The DNA has two flaws, and you (or your wife) will have to decide if they're deal breakers.
No microSD slot, and only 16GB (11GB usable) of internal memory. I still have over 8GB of memory still available, but I've uploaded my photos to DropBox, using DropSync (a program that'll automatically upload photos taken with your camera to your DropBox account, so you don't need to worry about losing them, and you can have it delete the photos from your cell phone automatically, after upload, to save space). I've downloaded and installed every app and game that I want/need.
The 2nd flaw is non-removable battery. However, for my needs, I've been able to leave the house at around 7:30am, with a full charge, use the DNA quite a bit all day, and return home at around 10pm with a little over 20% battery still remaining.
Bottom line... get your wife a DNA, and she'll have a couple of weeks to decide if it works for HER needs.
It's a fantastic phone!